René's URL Explorer Experiment


Title: High-performance scaling optimizations for large-scale datasets by svdrecbd · Pull Request #308 · pachterlab/kb_python · GitHub

Open Graph Title: High-performance scaling optimizations for large-scale datasets by svdrecbd · Pull Request #308 · pachterlab/kb_python

X Title: High-performance scaling optimizations for large-scale datasets by svdrecbd · Pull Request #308 · pachterlab/kb_python

Description: This PR introduces critical algorithmic and I/O optimizations to the kb_python core processing paths. By replacing sequential Python loops with vectorized operations and implementing memory-safe st...

Open Graph Description: This PR introduces critical algorithmic and I/O optimizations to the kb_python core processing paths. By replacing sequential Python loops with vectorized operations and implementing memory-safe st...

X Description: This PR introduces critical algorithmic and I/O optimizations to the kb_python core processing paths. By replacing sequential Python loops with vectorized operations and implementing memory-safe st...

Opengraph URL: https://github.com/pachterlab/kb_python/pull/308

X: @github

direct link

Domain: patch-diff.githubusercontent.com

route-pattern/_view_fragments/voltron/pull_requests/show/:user_id/:repository/:id/pull_request_layout(.:format)
route-controllervoltron_pull_requests_fragments
route-actionpull_request_layout
fetch-noncev2:94d70057-a90d-b780-ab3d-f6435cc91375
current-catalog-service-hashae870bc5e265a340912cde392f23dad3671a0a881730ffdadd82f2f57d81641b
request-idD906:97B7D:2F34B3:3D922A:698D294A
html-safe-noncebf923a015f48f06369ede65acf5d8a2d542bd357462c821518508c091c6f9f90
visitor-payloadeyJyZWZlcnJlciI6IiIsInJlcXVlc3RfaWQiOiJEOTA2Ojk3QjdEOjJGMzRCMzozRDkyMkE6Njk4RDI5NEEiLCJ2aXNpdG9yX2lkIjoiOTA4MDg1MjE0NzQzMjQwMTIyNiIsInJlZ2lvbl9lZGdlIjoiaWFkIiwicmVnaW9uX3JlbmRlciI6ImlhZCJ9
visitor-hmac31bbc746ecba7942bca425aa7a29bb87b3773aacc694560b887a6ac58f58ee43
hovercard-subject-tagpull_request:3229747974
github-keyboard-shortcutsrepository,pull-request-list,pull-request-conversation,pull-request-files-changed,copilot
google-site-verificationApib7-x98H0j5cPqHWwSMm6dNU4GmODRoqxLiDzdx9I
octolytics-urlhttps://collector.github.com/github/collect
analytics-location///voltron/pull_requests_fragments/pull_request_layout
fb:app_id1401488693436528
apple-itunes-appapp-id=1477376905, app-argument=https://github.com/_view_fragments/voltron/pull_requests/show/pachterlab/kb_python/308/pull_request_layout
twitter:imagehttps://opengraph.githubassets.com/6cdc56515d0ea08d97fefbdea3294c97a3f66ba74b704d19970a9fc3f0ceb3f8/pachterlab/kb_python/pull/308
twitter:cardsummary_large_image
og:imagehttps://opengraph.githubassets.com/6cdc56515d0ea08d97fefbdea3294c97a3f66ba74b704d19970a9fc3f0ceb3f8/pachterlab/kb_python/pull/308
og:image:altThis PR introduces critical algorithmic and I/O optimizations to the kb_python core processing paths. By replacing sequential Python loops with vectorized operations and implementing memory-safe st...
og:image:width1200
og:image:height600
og:site_nameGitHub
og:typeobject
og:author:usernamesvdrecbd
hostnamegithub.com
expected-hostnamegithub.com
Nonec25395580e1e3bf82d705e0982a1b24255366088720fef945f1493d5e3e67954
turbo-cache-controlno-preview
go-importgithub.com/pachterlab/kb_python git https://github.com/pachterlab/kb_python.git
octolytics-dimension-user_id10359946
octolytics-dimension-user_loginpachterlab
octolytics-dimension-repository_id215165758
octolytics-dimension-repository_nwopachterlab/kb_python
octolytics-dimension-repository_publictrue
octolytics-dimension-repository_is_forkfalse
octolytics-dimension-repository_network_root_id215165758
octolytics-dimension-repository_network_root_nwopachterlab/kb_python
turbo-body-classeslogged-out env-production page-responsive
disable-turbofalse
browser-stats-urlhttps://api.github.com/_private/browser/stats
browser-errors-urlhttps://api.github.com/_private/browser/errors
release1fa2bc33fc715bfb2cb9dd8a9cad4f811c16c371
ui-targetfull
theme-color#1e2327
color-schemelight dark

Links:

Skip to contenthttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308#start-of-content
https://patch-diff.githubusercontent.com/
Sign in https://patch-diff.githubusercontent.com/login?return_to=https%3A%2F%2Fgithub.com%2Fpachterlab%2Fkb_python%2Fpull%2F308
GitHub CopilotWrite better code with AIhttps://github.com/features/copilot
GitHub SparkBuild and deploy intelligent appshttps://github.com/features/spark
GitHub ModelsManage and compare promptshttps://github.com/features/models
MCP RegistryNewIntegrate external toolshttps://github.com/mcp
ActionsAutomate any workflowhttps://github.com/features/actions
CodespacesInstant dev environmentshttps://github.com/features/codespaces
IssuesPlan and track workhttps://github.com/features/issues
Code ReviewManage code changeshttps://github.com/features/code-review
GitHub Advanced SecurityFind and fix vulnerabilitieshttps://github.com/security/advanced-security
Code securitySecure your code as you buildhttps://github.com/security/advanced-security/code-security
Secret protectionStop leaks before they starthttps://github.com/security/advanced-security/secret-protection
Why GitHubhttps://github.com/why-github
Documentationhttps://docs.github.com
Bloghttps://github.blog
Changeloghttps://github.blog/changelog
Marketplacehttps://github.com/marketplace
View all featureshttps://github.com/features
Enterpriseshttps://github.com/enterprise
Small and medium teamshttps://github.com/team
Startupshttps://github.com/enterprise/startups
Nonprofitshttps://github.com/solutions/industry/nonprofits
App Modernizationhttps://github.com/solutions/use-case/app-modernization
DevSecOpshttps://github.com/solutions/use-case/devsecops
DevOpshttps://github.com/solutions/use-case/devops
CI/CDhttps://github.com/solutions/use-case/ci-cd
View all use caseshttps://github.com/solutions/use-case
Healthcarehttps://github.com/solutions/industry/healthcare
Financial serviceshttps://github.com/solutions/industry/financial-services
Manufacturinghttps://github.com/solutions/industry/manufacturing
Governmenthttps://github.com/solutions/industry/government
View all industrieshttps://github.com/solutions/industry
View all solutionshttps://github.com/solutions
AIhttps://github.com/resources/articles?topic=ai
Software Developmenthttps://github.com/resources/articles?topic=software-development
DevOpshttps://github.com/resources/articles?topic=devops
Securityhttps://github.com/resources/articles?topic=security
View all topicshttps://github.com/resources/articles
Customer storieshttps://github.com/customer-stories
Events & webinarshttps://github.com/resources/events
Ebooks & reportshttps://github.com/resources/whitepapers
Business insightshttps://github.com/solutions/executive-insights
GitHub Skillshttps://skills.github.com
Documentationhttps://docs.github.com
Customer supporthttps://support.github.com
Community forumhttps://github.com/orgs/community/discussions
Trust centerhttps://github.com/trust-center
Partnershttps://github.com/partners
GitHub SponsorsFund open source developershttps://github.com/sponsors
Security Labhttps://securitylab.github.com
Maintainer Communityhttps://maintainers.github.com
Acceleratorhttps://github.com/accelerator
Archive Programhttps://archiveprogram.github.com
Topicshttps://github.com/topics
Trendinghttps://github.com/trending
Collectionshttps://github.com/collections
Enterprise platformAI-powered developer platformhttps://github.com/enterprise
GitHub Advanced SecurityEnterprise-grade security featureshttps://github.com/security/advanced-security
Copilot for BusinessEnterprise-grade AI featureshttps://github.com/features/copilot/copilot-business
Premium SupportEnterprise-grade 24/7 supporthttps://github.com/premium-support
Pricinghttps://github.com/pricing
Search syntax tipshttps://docs.github.com/search-github/github-code-search/understanding-github-code-search-syntax
documentationhttps://docs.github.com/search-github/github-code-search/understanding-github-code-search-syntax
Sign in https://patch-diff.githubusercontent.com/login?return_to=https%3A%2F%2Fgithub.com%2Fpachterlab%2Fkb_python%2Fpull%2F308
Sign up https://patch-diff.githubusercontent.com/signup?ref_cta=Sign+up&ref_loc=header+logged+out&ref_page=%2F%3Cuser-name%3E%2F%3Crepo-name%3E%2Fvoltron%2Fpull_requests_fragments%2Fpull_request_layout&source=header-repo&source_repo=pachterlab%2Fkb_python
Reloadhttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
Reloadhttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
Reloadhttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
pachterlab https://patch-diff.githubusercontent.com/pachterlab
kb_pythonhttps://patch-diff.githubusercontent.com/pachterlab/kb_python
Notifications https://patch-diff.githubusercontent.com/login?return_to=%2Fpachterlab%2Fkb_python
Fork 28 https://patch-diff.githubusercontent.com/login?return_to=%2Fpachterlab%2Fkb_python
Star 181 https://patch-diff.githubusercontent.com/login?return_to=%2Fpachterlab%2Fkb_python
Code https://patch-diff.githubusercontent.com/pachterlab/kb_python
Issues 1 https://patch-diff.githubusercontent.com/pachterlab/kb_python/issues
Pull requests 3 https://patch-diff.githubusercontent.com/pachterlab/kb_python/pulls
Actions https://patch-diff.githubusercontent.com/pachterlab/kb_python/actions
Security 0 https://patch-diff.githubusercontent.com/pachterlab/kb_python/security
Insights https://patch-diff.githubusercontent.com/pachterlab/kb_python/pulse
Code https://patch-diff.githubusercontent.com/pachterlab/kb_python
Issues https://patch-diff.githubusercontent.com/pachterlab/kb_python/issues
Pull requests https://patch-diff.githubusercontent.com/pachterlab/kb_python/pulls
Actions https://patch-diff.githubusercontent.com/pachterlab/kb_python/actions
Security https://patch-diff.githubusercontent.com/pachterlab/kb_python/security
Insights https://patch-diff.githubusercontent.com/pachterlab/kb_python/pulse
Sign up for GitHub https://patch-diff.githubusercontent.com/signup?return_to=%2Fpachterlab%2Fkb_python%2Fissues%2Fnew%2Fchoose
terms of servicehttps://docs.github.com/terms
privacy statementhttps://docs.github.com/privacy
Sign inhttps://patch-diff.githubusercontent.com/login?return_to=%2Fpachterlab%2Fkb_python%2Fissues%2Fnew%2Fchoose
Jump to bottomhttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308#issue-comment-box
svdrecbdhttps://patch-diff.githubusercontent.com/svdrecbd
pachterlab:masterhttps://patch-diff.githubusercontent.com/pachterlab/kb_python/tree/master
svdrecbd:optimize-scaling-and-parityhttps://patch-diff.githubusercontent.com/svdrecbd/kb_python/tree/optimize-scaling-and-parity
High-performance scaling optimizations for large-scale datasets https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308#top
svdrecbdhttps://patch-diff.githubusercontent.com/svdrecbd
pachterlab:masterhttps://patch-diff.githubusercontent.com/pachterlab/kb_python/tree/master
svdrecbd:optimize-scaling-and-parityhttps://patch-diff.githubusercontent.com/svdrecbd/kb_python/tree/optimize-scaling-and-parity
Conversation 3 https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
Commits 1 https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308/commits
Checks 0 https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308/checks
Files changed https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308/files
Please reload this pagehttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
https://github.co/hiddenchars
https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/{{ revealButtonHref }}
https://patch-diff.githubusercontent.com/svdrecbd
svdrecbdhttps://patch-diff.githubusercontent.com/svdrecbd
Jan 31, 2026https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308#issue-3877968397
https://cf.10xgenomics.com/samples/cell-exp/3.0.0/pbmc_10k_v3/pbmc_10k_v3_raw_feature_bc_matrix.tar.gzhttps://cf.10xgenomics.com/samples/cell-exp/3.0.0/pbmc_10k_v3/pbmc_10k_v3_raw_feature_bc_matrix.tar.gz
Please reload this pagehttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
https://patch-diff.githubusercontent.com/svdrecbd
Optimize validation, matrix operations, reference generation, and pro…https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308/commits/7005275c31b3cfa546a7634baede73641d839125
7005275https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308/commits/7005275c31b3cfa546a7634baede73641d839125
https://patch-diff.githubusercontent.com/svdrecbd
svdrecbdhttps://patch-diff.githubusercontent.com/svdrecbd
Feb 6, 2026https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308#issuecomment-3857527162
Please reload this pagehttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
https://patch-diff.githubusercontent.com/Yenaled
Yenaledhttps://patch-diff.githubusercontent.com/Yenaled
Feb 6, 2026https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308#issuecomment-3857531961
Please reload this pagehttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
https://patch-diff.githubusercontent.com/svdrecbd
svdrecbdhttps://patch-diff.githubusercontent.com/svdrecbd
Feb 6, 2026https://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308#issuecomment-3857536467
Please reload this pagehttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
Sign up for freehttps://patch-diff.githubusercontent.com/join?source=comment-repo
Sign in to commenthttps://patch-diff.githubusercontent.com/login?return_to=https%3A%2F%2Fgithub.com%2Fpachterlab%2Fkb_python%2Fpull%2F308
Please reload this pagehttps://patch-diff.githubusercontent.com/pachterlab/kb_python/pull/308
https://patch-diff.githubusercontent.com/svdrecbd
https://patch-diff.githubusercontent.com/Yenaled
https://github.com
Termshttps://docs.github.com/site-policy/github-terms/github-terms-of-service
Privacyhttps://docs.github.com/site-policy/privacy-policies/github-privacy-statement
Securityhttps://github.com/security
Statushttps://www.githubstatus.com/
Communityhttps://github.community/
Docshttps://docs.github.com/
Contacthttps://support.github.com?tags=dotcom-footer

Viewport: width=device-width

URLs of crawlers that visited me.