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| README.md | https://github.com/soedinglab/MMseqs2/blob/master/README.md |
| azure-pipelines.yml | https://github.com/soedinglab/MMseqs2/blob/master/azure-pipelines.yml |
| azure-pipelines.yml | https://github.com/soedinglab/MMseqs2/blob/master/azure-pipelines.yml |
| README | https://github.com/soedinglab/mmseqs2 |
| MIT license | https://github.com/soedinglab/mmseqs2 |
| https://github.com/soedinglab/mmseqs2#mmseqs2-ultra-fast-and-sensitive-sequence-search-and-clustering-suite |
| https://github.com/soedinglab/mmseqs2#publications |
| Steinegger M and Soeding J. MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets. Nature Biotechnology, doi: 10.1038/nbt.3988 (2017) | https://www.nature.com/articles/nbt.3988 |
| Steinegger M and Soeding J. Clustering huge protein sequence sets in linear time. Nature Communications, doi: 10.1038/s41467-018-04964-5 (2018) | https://www.nature.com/articles/s41467-018-04964-5 |
| Mirdita M, Steinegger M and Soeding J. MMseqs2 desktop and local web server app for fast, interactive sequence searches. Bioinformatics, doi: 10.1093/bioinformatics/bty1057 (2019) | https://academic.oup.com/bioinformatics/article/35/16/2856/5280135 |
| Mirdita M, Steinegger M, Breitwieser F, Soding J, Levy Karin E: Fast and sensitive taxonomic assignment to metagenomic contigs. Bioinformatics, doi: 10.1093/bioinformatics/btab184 (2021) | https://doi.org/10.1093/bioinformatics/btab184 |
| Kallenborn F, Chacon A, Hundt C, Sirelkhatim H, Didi K, Cha S, Dallago C, Mirdita M, Schmidt B, Steinegger M: GPU-accelerated homology search with MMseqs2. Nature Methods, doi: 10.1038/s41592-025-02819-8 (2025) | https://www.nature.com/articles/s41592-025-02819-8 |
| https://anaconda.org/bioconda/mmseqs2 |
| https://github.com/soedinglab/mmseqs2/releases/latest |
| https://biocontainers.pro/#/tools/mmseqs2 |
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| https://github.com/soedinglab/mmseqs2#documentation |
| GitHub Wiki | https://github.com/soedinglab/mmseqs2/wiki |
| PDF file | https://mmseqs.com/latest/userguide.pdf |
| pandoc | https://github.com/jgm/pandoc |
| tutorials | https://github.com/soedinglab/MMseqs2/wiki/Tutorials |
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| https://github.com/soedinglab/mmseqs2#installation |
| compiling from source | https://github.com/soedinglab/MMseqs2/wiki#installation |
| mmseqs.com/latest | https://mmseqs.com/latest |
| Homebrew | https://github.com/Homebrew/brew |
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| https://github.com/soedinglab/mmseqs2#getting-started |
| documentation | https://github.com/soedinglab/mmseqs2/wiki |
| https://github.com/soedinglab/mmseqs2#cluster |
| clustering format | https://github.com/soedinglab/mmseqs2/wiki#clustering-format |
| clustering criteria | https://github.com/soedinglab/MMseqs2/wiki#clustering-criteria |
| https://github.com/soedinglab/mmseqs2#search |
| GPU-accelerated search | https://github.com/soedinglab/MMseqs2/wiki#gpu-accelerated-search |
| Downloading databases | https://github.com/soedinglab/mmseqs2/wiki#downloading-databases |
| setting sensitivity -s parameter | https://github.com/soedinglab/mmseqs2/wiki#set-sensitivity--s-parameter |
| here | https://github.com/soedinglab/MMseqs2/wiki#how-to-control-the-speed-of-the-search |
| output columns | https://github.com/soedinglab/mmseqs2/wiki#custom-alignment-format-with-convertalis |
| estimates | https://github.com/soedinglab/MMseqs2/wiki#how-does-mmseqs2-compute-the-sequence-identity |
| https://github.com/soedinglab/mmseqs2#taxonomy |
| BLAST | https://github.com/soedinglab/MMseqs2/wiki#create-a-sequence-database-with-taxonomic-information-from-an-existing-blast-database |
| SILVA | https://github.com/soedinglab/MMseqs2/wiki#create-a-sequence-database-with-taxonomic-information-for-silva |
| custom taxonomical | https://github.com/soedinglab/MMseqs2/wiki#manually-annotate-a-sequence-database-with-taxonomic-information |
| databases workflow | https://github.com/soedinglab/mmseqs2/wiki#downloading-databases |
| taxonomy format | https://github.com/soedinglab/MMseqs2/wiki#taxonomy-format |
| classification | https://github.com/soedinglab/MMseqs2/wiki#taxonomy-assignment-using-mmseqs-taxonomy |
| https://github.com/soedinglab/mmseqs2#supported-search-modes |
| Translated searches | https://github.com/soedinglab/MMseqs2/wiki#translated-sequence-searching |
| Iterative increasing sensitivity searches | https://github.com/soedinglab/MMseqs2/wiki#how-to-find-the-best-hit-the-fastest-way |
| Taxonomic assignment | https://github.com/soedinglab/MMseqs2/wiki#taxonomy-assignment-using-mmseqs-taxonomy |
| very similar sequence matches | https://github.com/soedinglab/MMseqs2/wiki#mapping-very-similar-sequences-using-mmseqs-map |
| profile databases such as the PFAM | https://github.com/soedinglab/MMseqs2/wiki#how-to-create-a-target-profile-database-from-pfam |
| Reciprocal best hits search | https://github.com/soedinglab/MMseqs2/wiki#reciprocal-best-hit-using-mmseqs-rbh |
| Web search API and user interface | https://github.com/soedinglab/MMseqs2-App |
| https://github.com/soedinglab/mmseqs2#memory-requirements |
| https://github.com/soedinglab/mmseqs2#how-to-run-mmseqs2-on-multiple-servers-using-mpi |
| https://github.com/soedinglab/mmseqs2#contributors |
|
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| mmseqs.com | https://mmseqs.com |
|
bioinformatics
| https://github.com/topics/bioinformatics |
|
taxonomy
| https://github.com/topics/taxonomy |
|
metagenomics
| https://github.com/topics/metagenomics |
|
alignment
| https://github.com/topics/alignment |
|
sequence-clustering
| https://github.com/topics/sequence-clustering |
|
profile-search
| https://github.com/topics/profile-search |
|
sequence-search
| https://github.com/topics/sequence-search |
|
linclust
| https://github.com/topics/linclust |
|
mmseqs
| https://github.com/topics/mmseqs |
|
blast
| https://github.com/topics/blast |
|
Readme
| https://github.com/soedinglab/mmseqs2#readme-ov-file |
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|
MMseqs2 Release 18-8cc5c
Latest
Jul 27, 2025
| https://github.com/soedinglab/MMseqs2/releases/tag/18-8cc5c |
| + 18 releases | https://github.com/soedinglab/MMseqs2/releases |
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