René's URL Explorer Experiment

{"@context":"https://schema.org","@type":"DiscussionForumPosting","headline":"Running script with CLR a second time gives \"RuntimeError: Failed to initialize Python.Runtime.dll\"","articleBody":"### Environment\r\n\r\n-   Pythonnet version: 3.0.1\r\n-   Python version: 3.10.9\r\n-   Operating System: Windows 11\r\n-   .NET Runtime: 4.8\r\n\r\n### Details\r\n\r\n-   Describe what you were trying to get done.\r\n\r\nI'm using the Spyder IDE with Conda.  When I run a Python script to import CLR and add references, the first time it works.  However, if I re-run, then the second time it fails with an error, and I have to restart my Spyder IDE for it to work again.\r\n\r\n-   What commands did you run to trigger this issue? If you can provide a\r\n    [Minimal, Complete, and Verifiable example](http://stackoverflow.com/help/mcve)\r\n    this will help us understand the issue.\r\n\r\nRunning this once, works fine.  Run it a second time, get an error\r\n\r\n```\r\nimport clr\r\n\r\nclr.AddReference('System.Linq')\r\nclr.AddReference('System.Collections')\r\n```\r\n\r\n-   If there was a crash, please include the traceback here.\r\n\r\n```\r\nReloaded modules: CLR, clr\r\nTraceback (most recent call last):\r\n\r\n  File ~\\miniconda3\\envs\\spyder-env\\lib\\site-packages\\spyder_kernels\\py3compat.py:356 in compat_exec\r\n    exec(code, globals, locals)\r\n\r\n  File c:\\users\\...\\test.py:2\r\n    import clr\r\n\r\n  File ~\\miniconda3\\envs\\spyder-env\\lib\\site-packages\\clr.py:6\r\n    load()\r\n\r\n  File ~\\miniconda3\\envs\\spyder-env\\lib\\site-packages\\pythonnet\\__init__.py:144 in load\r\n    raise RuntimeError(\"Failed to initialize Python.Runtime.dll\")\r\n\r\nRuntimeError: Failed to initialize Python.Runtime.dll\r\n\r\n\r\nFailed to initialize pythonnet: System.InvalidOperationException: This property must be set before runtime is initialized\r\n   at Python.Runtime.Runtime.set_PythonDLL(String value)\r\n   at Python.Runtime.Loader.Initialize(IntPtr data, Int32 size)\r\n   at Python.Runtime.Runtime.set_PythonDLL(String value)\r\n   at Python.Runtime.Loader.Initialize(IntPtr data, Int32 size)\r\n```\r\n","author":{"url":"https://github.com/szhuge-ci","@type":"Person","name":"szhuge-ci"},"datePublished":"2023-02-04T00:43:55.000Z","interactionStatistic":{"@type":"InteractionCounter","interactionType":"https://schema.org/CommentAction","userInteractionCount":5},"url":"https://github.com/2099/pythonnet/issues/2099"}